Automated Bone Scan Index (BSI): From Research to Global Clinical Impact
The Automated Bone Scan Index (BSI), now available worldwide through GE and Siemens clinical platforms, began as a research initiative by our group in 2005.
We systematically developed and validated AI methods for bone scan analysis, resulting in over 20 peer-reviewed publications and two PhD theses (Sadik and Kaboteh). The clinical translation of our work was achieved in collaboration with EXINI Diagnostics and international partners, including Memorial Sloan Kettering Cancer Center in New York.
BSI quantifies skeletal tumor burden and has proven prognostic value: BSI at diagnosis is a strong predictor of survival, and changes in BSI correlate closely with treatment response.
“We’re proud to have contributed to the development of BSI—now a globally used imaging biomarker supporting both clinical care and trials.”
CardioRepo: A Cardiac Toolbox for Japanese Patients
CardioRepo is a cardiac imaging toolbox used in hundreds of hospitals across Japan. It exemplifies how international collaboration—between academia and industry—can result in clinically impactful tools.
This project originated in 2005 as part of a PhD project and grew through ongoing collaboration with Kanazawa University in Japan. Based on our research, EXINI Diagnostics developed CardioRepo, tailored specifically to Japanese patient populations.
“I’m grateful to have been part of a truly international team that not only advanced science but delivered tools benefiting patients directly.”
PET/CT and CT in Prostate Cancer
As new treatments for prostate cancer emerge, precise diagnostic tools become increasingly important. PET/CT is now a critical component in prostate cancer diagnosis, and CT is routinely used for radiation treatment planning.
Our group has contributed to tool development that supports the manual and AI-assisted interpretation of prostate cancer imaging. These efforts have laid the groundwork for AI-based tools that are already in clinical use—and further improvements are underway.
“We’re proud that our research has contributed to clinically used AI tools—progress continues as we build on this foundation.”
The Nuclear IMaging group at the Sahlgrenska Academy